Prof. Michael Bursztyn
Israel
I am an Internist, with a lifelong interest, practice, and research in hypertension. My interest in the subject were initiated and sustained by Prof. Talma Rosenthal during years we worked together in Sheba Medical Center, strengthened during my fellowship with Profs. Harry and Irene Gavras in Boston. Later I have returned to Israel to Hadassah-Hebrew University Medical Center, Mount-Scopus, Jerusalem , where Prof. Drori Ben-Ishay had invited me to work with him, where I am since 1989 and am currently head of the hypertension unit a Professor of Medicine, and am involved in teaching and practice of internal medicine and hypertension. I have been recognized as a ESH hypertension specialist and my unit as an ESH Excellence Center. I has served some years as the Chairman of the Israel Hypertension Society, and am serving on the editorial board of Hypertension, Journal of Human Hypertension and in the past Journal of Hypertension, and am an associate editor of Cardiorenal Medicine. I had contributed to hypertension research in both clinical and experimental domains: 1) Analysis of ambulatory blood pressure measurements with particular emphasis on the impact of sleep including daytime naps and nocturnal awakenings on the dipping phenomenon. My initial observations of these effects were repeatedly confirmed by other investigators. 2) Epidemiologic studies: in the elderly, including effects, or rather lack of effect of hypertension or blood pressure on mortality in very elderly community dwelling subjects. Also contributed to understanding discrepancy between the controlled HYVET study results to those of many observational studies by demonstrating that only 9% would have been HYVET eligible. In Ethiopian immigrants showing a high rate of hypertension in young immigrants related to insulin resistance despite remarkably low BMI. I had introduced a new concept of daytime napping as a risk factor, which was met with wide skepticism but now confirmed by subsequent research and 3 met analyses. 3) In experimental hypertension I have contributed to understanding the role of insulin resistance to hypertension via the NO system which also led to an exogenous hyperinsulinemia pregnancy induced model, effects on NOS and endothelin systems, and subsequent offspring hypertension. I have participated in discovering muscle proteins in endovascular trophoblasts and their functional role in normal pregnant rats, an ongoing research. I believe that my broad experience both in clinical and experimental hypertension, ability to perform such research in a relatively low resource environment over years, may be of relevance to the International Society of Hypertension Scientific Council.